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Nitrates You Shouldn’t Take With ED Meds

The Nitrates You Shouldn’t Take With ED Meds

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Written By-Molly Wilson
 • Published: 21/06/2025
• Updated: 21/06/2025

When you have erectile dysfunction and are probably using medicines like Sildenafil or Tadalafil, it is essential to follow a list of safety tips. You must have seen how the doctors tell you to follow a few simple rules of dosage and disallow the use of certain medicines and other substances.

Well, if you have noted carefully, you must have found how the doctors are not willing to recommend any medicine that contains Nitrates along with ED pills. Do you ever wonder why the doctors do it?

Well, in this blog we are going to tell you in detail about the risk of using any Nitrates pills with ED meds like Cenforce 100. We will tell you how nitrate medicines may interact, what sort of side effects or health risks they carry, and the brands you need to avoid the most.

We are also going to give you a list of food items that are also loaded with Nitrates, the ones you should avoid taking with any ED pill.


Why Do Doctors Avoid Recommending Nitrate Medicine With ED Drugs?


The reason is simple: it is not safe. Through different studies and findings, it has been seen that medicines that have a compound of Nitrates in them may pave the way for a major side effect.

Nitrate Medicine

It interacts heavily with all ED medicines like Cenforce 150 and increases the risks of a severe side effects. For example, a study done in the UK found that men taking a nitrate pill had major side effects after using the ED medicine within minutes. This was the sole reason why 80% of such males had severe side effects.


Nitrates Pills And ED Medicines- The Risks Involved


Through research, it has been found that taking an ED medicine with a nitrate pill or even when its action is active in your body, can cause many health issues.

Here is a list of some problems you may face if you take these two pills at the same time-

➯ Mild Issues

  • Headache
  • Dizziness
  • Nausea
  • Palpitations
  • Sweating
  • Numb feeling in the palms
  • Fatigue

➯ More Severe Issues

Scientists think that more severe health problems may occur if the interaction is very severe when you take a high dose of ED medicine like Cenforce 200mg with nitrate pills. These are-


Why Do Nitrates Interact With ED Pills?


Scientists did a study to find out why nitrate pills interact with ED drugs like Fildena. The finding shows how both drugs are capable of dilation in the arteries.

ED drugs dilate the arteries by inhibiting the PDE-5 Inhibitors hormones, increasing the effects of the cGMP enzyme, and activating nitric oxide, the main element behind dilation.

Drug Name Counseling Points

Erectile Dysfunction Medications

Sildenafil (Viagra) – DO NOT take nitrate medications with ED medications — This can cause a dangerous drop in blood pressure.
-Lifestyle interventions like exercise, weight loss, and healthy eating can help improve sexual function
Tadalafil (Cialis)
Avanafil (Stendra)
Vardenafil

Nitrate Medications

Nitroglycerin (Nitro-Dur, Nitrostat, others) – Sit or lie down before taking fast-acting nitrates to avoid dizziness or fainting
– Report any changes in your symptoms to your doctor
Isosorbide mononitrate (Monoket)
Isosorbine dinatrate (Bidil)

In a very similar way, nitrate medicines may also work the same way causing dilation.

This action can result in reducing your BP levels. As the BP, level drops fast and abruptly, you may notice changes in yourself. Here is a list-

  • Faster breathing
  • Abrupt heartbeat
  • Low pulse rate

Scientists even noted how less than 1% of men had gone unconscious because of the sudden and abrupt fall in BP levels. Hence, it is better to use ED drugs like Fildena 150 with care.


Types Of Nitrate Compounds That Show Chances Of Interaction

Through careful study, experts have been able to track and jot down a list of nitrate compound that reacts heavily with ED drugs and result in side effects. This are-

  1. Isosorbide mononitrate
  2. Isosorbide Nitrates
  3. Nitroglycerine

Along with this, there are a handful of other nitrate compounds that have shown mild interaction chances. If you want to know about them, get in touch with a doctor.


Nitrate Medicine Brands That Are Not Safe To Use With ED Pills


Let us now tell you about a list of a few nitrate medicine brands that you must never try to use with branded pills for ED like Vidalista 20

  • Nitrostat
  • Isordil
  • Monoket
  • Nitromist
  • Nitrol
  • Dilatrate SR

What To Tell The Doctor Before Using An ED Medicine?


Before you abruptly try to use an ED medicine like Vidalista 40, there are a couple of things that you have to tell the doctors. Here is a list-

  • Tell the doctors if you have low BP.
  • Tell the doctors when the last time was you have taken medicine for it was or if you are doing so daily right now.
  • Let the doctors check the brand of medicine to cure low BP along with its dose.

When Are Nitrates Medicines Generally Given To A Person?


So, you likely know by now that a nitrate medicine can perform badly with an ED medicine like Vidalista 60 and cause a major interaction and side effects. However, do you know when such nitrate medicines are given? Well, here is a list of some cases when the doctors can instruct you to use any nitrate medicine-

  • When you have a high BP
  • When you have recently gone through heart surgery
  • With a major cardiac disorder like aneurysm
  • When the doctors since there is a high chance of heart attack
  • When you suffer from angina or regular chest pain

Final Thoughts


Therefore, we hope you have been able to understand the criticality of taking a Nitrates pill with an ED drug. We hope you will never allow such a mistake to occur, as it can be costly and end up with severe side effects.


FAQs


Q. Where To Buy ED Pills?

Check out our online pharmacy Powpills and get some interesting discounts.

Q. I Had Previously Used Nitrates Pills, Is It Safe To Use ED Pills Now?

Most often, the doctors may not tell you to use ED pills in case you have used nitrate pills in less than 1 month.

Q. Can I Give A Few Hours Break Between A Nitrates And An ED Pill?

Maybe if taking a nitrate pill is necessary, the doctors will tell you to give a time gap between using an ED and a nitrate drug. This time gap has to be more than 10 to 12 hours at least.